Publications
In TOOsonix we are constantly working to expand our knowledge and expertise. We are committed to publish results that can assist our own company as well as our customers and partners to follow our mission: Helping people by use of high frequency HIFU.
We will continuously be adding publications as they are published and become publicly available. Please contact us for more information or to get copies of the available publications.
October 2023 – Peer reviewed paper published in Karger Case Reports in Dermatology (Karger AG).
Treatment of Cutaneous Neurofibromas in Patients with Neurofibromatosis Type 1
Bartosz Wozniaka,b , Torsten Boved, Tomasz Zawadad, Jacek Calikb,c
a Department of Dermatology and Venereology, Regional Specialist Hospital, Wroclaw, Kamienskiego 73A, 51-124 Wroclaw, Poland.
b Old Town Clinic, Wszystkich Swietych 2a, 50-127 Wroclaw, Poland.
c Department of Oncology, Academic Hospital Wroclaw, Borowska Street 213, 50-556 Wroclaw, Poland
d TOOsonix A/S, Agern Allé 1, 2970 Hoersholm, Denmark.
Link to open access paper here
April 2023 – Poster presentation – International Society for Therapeutic Ultrasound (ISTU) and the European Focused Ultrasound Charitable Society (EUFUS), Lyon France, April 17th – 20th 2023.
Opening new fields for focused ultrasound therapy: HIFU for dermatology.
Torsten Bove and Tomasz Zawada
TOOsonix A/S, Hoersholm, Denmark
Download Abstract here
See 5 – min video of the poster here
March 2023 – Peer reviewed paper published in IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control.
Head-to-head comparison of acoustic properties of lead-free and PZT based HIFU transducers operating at 12 MHz.
Tomasz Zawada1, Torsten Bove1, Rasmus Lou-Møller2, Erling Ringgaard2
1TOOsonix A/S, Hoersholm, Denmark
2CTS Ferroperm Piezoceramics A/S, Kvistgaard, Denmark
Link to paper here (contact us for copy)
December 2022 – Peer reviewed paper published in Proceddings of the 2022 IEEE International Ultrasonics Symposium (IUS).
Acoustic field of strongly focused HIFU transducer operating at 20 MHz – comparison of public domain numerical simulators with experimental observations.
Tomasz Zawada1, Torsten Bove1
1TOOsonix A/S, Hoersholm, Denmark
Link to abstract here (contact us for full copy)
October 2022 – Peer reviewed paper published in Karger Case Reports in Dermatology (Karger AG).
Treatment of Condylomata Acuminata Using a New Non-Vapor-Generating Focused Ultrasound Method following Imiquimod 5% Cream
Jacek Calik1, Tomasz Zawada2, Torsten Bove2.
1Old Town Clinic, Wroclaw, Poland
2TOOsonix A/S, Hoersholm, Denmark
Link to open access paper here
September 2022 – Peer reviewed paper published in Ultrasound in Medicine and Biology (Elsevier Inc.).
Lead-free HIFU Transducers
Tomasz Zawada1, Torsten Bove1, Konstantin Astafiev2, Erling Ringgaard2, Rasmus Lou-Moeller2.
1TOOsonix A/S, Hoersholm, Denmark
2CTS Ferroperm Piezoceramics A/S, Kvistgaard, Denmark
Link to open access paper here
September 2022 – Poster at EADV 2022 in Milano, Italy.
Treatment of Benign Skin Tumors by High Frequency Focused Ultrasound.
Bartosz Woźniak 1,2, Jacek Calik 1,3
1 Old Town Clinic, Wroclaw, Poland
2 Department of Dermatology and Venereology in Regional Specialist Hospital, Wroclaw, Poland
3 Lower Silesian Oncology Center, Wroclaw, Poland
Link to Poster (Contact us for copy)
March 2022 – Peer reviewed paper published in Ultrasound in Medicine and Biology (Elsevier Inc.).
Strongly focused HIFU transducers with simultaneous optical observation for treatment of skin at 20 MHz.
Tomasz Zawada1 and Torsten Bove1
1TOOsonix A/S, Hoersholm, Denmark
Link to open access paper here
January 2022 – Peer-reviewed paper published in Clinical, Cosmetic and Investigational Dermatology (DovePress Ltd).
Treatment of Seborrheic Keratosis by High Frequency Focused Ultrasound – An Early Experience with 11 Consecutive Cases.
Jacek Calik1, Monika Migdal1, Tomasz Zawada2, Torsten Bove2.
1Old Town Clinic, Wroclaw, Poland
2TOOsonix A/S, Hoersholm, Denmark
Link to open access paper here
December 2021 – Peer-reviewed paper published in Dermatology (Karger AG, Basel, CH).
Efficacy Assessment of the High-Frequency High-Intensity Focused Ultrasound as a New Treatment for Actinic Keratosis.
Seyed Jafari S.M1, Cazzaniga S1, Bossart S1, Feldmeyer L1, Pelloni L1, van Rhyn M1, Angermeier S1, Adatto M1, Hunger R.E1, Heidemeyer K1.
1Dept of Dermatology, Inselspital, Bern University Hospital, Bern, Switzerland
Link to paper here (contact us for copy)
December 2021 – Peer-reviewed paper published in Journal of Cosmetic Dermatology (John Wiley and Sons Inc).
Treatment of superficial benign vascular tumors by high intensity focused ultrasound: Observations in two illustrative cases.
Jacek Calik1, Tomasz Zawada2, Torsten Bove2.
1Old Town Clinic, Wroclaw, Poland
2TOOsonix A/S, Hoersholm, Denmark
Link to open access paper here
October 2021 – Internal Whitepaper on off-label use of medical devices.
Off-label use of medical devices.
This is an internal whitepaper describing the key characteristics and differences between on-label and off-label use of medical devices. It gives general guidelines for the doctor’s responsibilities and options in the two cases.
Link to pdf document here
July 2021 – Peer-reviewed paper published in Case reports in Dermatology (S. Karger AG, Basel, CH).
Removal of Common Warts by High-Intensity Focused Ultrasound: An Introductory Observation.
Torsten Bove1, Tomasz Zawada1, Alexander Jessen1, Mattia Poli1, Jørgen Serup2.
1TOOsonix A/S, Hoersholm, Denmark
2Bispebjerg University Hospital, Copenhagen Denmark
Link to open access paper here
June 2020 – Peer-reviewed paper published in Skin Research and Technology (John Wiley & Sons, Inc.)
High-frequency (20 MHz) high-intensity focused ultrasound: New Treatment of actinic keratosis, basal cell carcinoma, and Kaposi sarcoma. An open-label exploratory study.
Joergen Serup1, Torsten Bove2, Tomasz Zawada2, Alexander Jessen2, Mattia Poli2.
1Bispebjerg University Hospital, Copenhagen Denmark
2TOOsonix A/S, Hoersholm, Denmark
Link to open access paper here.
June 2020 – Peer-reviewed paper published in Skin Research and Technology (John Wiley & Sons, Inc.)
High-frequency (20 MHz) high-intensity focused ultrasound: New ablative method for color-independent tattoo removal in 1-3 sessions—An open-label exploratory study.
Joergen Serup1, Torsten Bove2, Tomasz Zawada2, Alexander Jessen2, Mattia Poli2.
1Bispebjerg University Hospital, Copenhagen Denmark
2TOOsonix A/S, Hoersholm, Denmark
Link to open access paper here.
March 2020 – Peer-reviewed paper in Skin Research and Technology (John Wiley & Sons, Inc.)
High-frequency (20-MHz) high-intensity focused ultrasound (HIFU) system for dermal intervention: A 12‐week local tolerance study in minipigs.
Susi Soegaard1, Vibeke Aarup1, Joergen Serup2, Torsten Bove3, Tomasz Zawada3, Alexander Jessen3, Mattia Poli3.
1Citoxlab Scantox A/S, Lille Skensved, Denmark
2Bispebjerg University Hospital, Copenhagen Denmark
3TOOsonix A/S, Hoersholm, Denmark
Link to original paper. (contact us for copy)
January 2019 – Peer-reviewed paper in Skin Research and Technology (John Wiley & Sons, Inc.)
High-frequency (20-MHz) high-intensity focused ultrasound (HIFU) system for dermal intervention: Preclinical evaluation in skin equivalents.
Torsten Bove1, Tomasz Zawada1, Alexander Jessen1, Mattia Poli1, Jørgen Serup2.
1TOOsonix A/S, Hoersholm, Denmark
2Bispebjerg University Hospital, Copenhagen Denmark
Link to original paper. (contact us for copy)
September 2018 – Whitepaper made in cooperation with equipment supplier
Characterisation of PZT using an Omicron Bode100.
This is a white-paper that the describes the key characteristics of piezoelectric ceramics and how to measure it using a commercially available and cost effective equipment supplied by Omicron Lab